高等有机化学-反应与合成(第五版) 目录

PrefaceAcknowledgmentandPersonalStatementIntroductionChapter1.AlkylationofEnolatesandOtherCarbonNucleophilesIntroduction1.1.GenerationandPropertiesofEnolatesandOtherStabilizedCarbanions1.1.1.GenerationofEnolatesbyDeprotonation1.1.2.RegioselectivityandStereoselectivityinEnolateFormationfromKetonesandEsters1.1.3.OtherMeansofGeneratingEnolates1.1.4.SolventEffectsonEnolateStructureandReactivity1.2.AlkylationofEnolates1.2.1.AlkylationofHighlyStabilizedEnolates1.2.2.AlkylationofKetoneEnolates1.2.3.AlkylationofAldehydes,Esters,CarboxylicAcids,Amides,andNitriles1.2.4.GenerationandAlkylationofDianions1.2.5.IntramolecularAlkylationofEnolates1.2.6.ControlofEnantioselectivityinAlkylationReac:ions1.3.TheNitrogenAnalogsofEnolsandEnolates:EnaminesandImineAnionsGeneralReferencesProblemsChapter2.ReactionsofCarbonNucleophileswithCarbonylCompoundsIntroduction2.1.AldolAdditionandCondensationReactions2.1.1.TheGeneralMechanism2.1.2.ControlofRegio-andStereoselectivityofAldolReactionsofAldehydesandKetones2.1.3.AldolAdditionReactionsofEnolatesofEstersandOtherCarbonylDerivatives2.1.4.TheMukaiyamaAldolReaction2.1.5.ControlofFacialSelectivityinAldolandMukaiyamaAldolReactions2.1.6.IntramolecularAldolReactionsandtheRobinsonAnnulation2.2.AdditionReactionsofIminesandIminiumIons2.2.1.TheMannichReaction2.2.2.AdditionstoN-AcylIminiumIons2.2.3.Amine-CatalyzedCondensationReactions2.3.AcylationofCarbonNucleophiles2.3.1.ClaisenandDieckmannCondensationReactions2.3.2.AcylationofEnolatesandOtherCarbonNucleophiles2.4.OlefinationReactionsofStabilizedCarbonNucleophiles2.4.1.TheWittigandRelatedReactionsofPhosphorus-StabilizedCarbonNucleophiles2.4.2.Reactionsofa-TrimethyisilylcarbanionswithCarbonylCompounds2.4.3.TheJuliaOlefinationReaction2.5.ReactionsProceedingbyAddition-Cyclization2.5.1.SulfurYiidesandRelatedNucleophiles2.5.2.NucleophilicAddition-Cyclizationofot-Haloesters2.6.ConjugateAdditionbyCarbonNucleophiles2.6.1.ConjugateAdditionofEnolates2.6.2.ConjugateAdditionwithTandemAlkylation2.6.3.ConjugateAdditionbyEnolateEquivalents2.6.4.ControlofFacialSelectivityinConjugateAdditionReactions2.6.5.ConjugateAdditionofOrganometallicReagents2.6.6.ConjugateAdditionofCyanideIonGeneralReferencesProblemsChapter3.FunctionalGroupInterconversionbySubstitution,IncludingProtectionandDeprotectionIntroduction3.1.ConversionofAlcoholstoAlkylatingAgents3.1.1.SulfonateEsters3.1.2.HalidesChapter4.ElectrophilicAdditionstoCarbon-CarbonMultipleBondsChapter5.ReductionofCarbon-CarbonMultipleBonds,CarbonylCroups,andOtherFunctionalGroupsChapter6.ConcertedCycloadditions,UnimolecularRearrangements,andThermalEliminationsChapter7.OrganometallicCompoundsofGroupIandIIMetalsChapter8.ReactionsInvolvingTransitionMetalsChapter9.Carbon-CarbonBond-FormingReactionsofCompoundsofBoron,Silcon,andTinChapter10.ReactionsInvolvingCarbocations,Carbenes,andRadicalsandReactiveIntermediatesChapter11.AromaticSubstitutionReactionsChapter12.OxidationsChapter13.MultistepSynthesesReferencesIndex

高等有机化学-反应与合成(第五版) 本书特色

《高等有机化学：反应与合成》(第5版)可供有机化学、药物化学和生物化学等专业的高年级本科生、研究生以及相关领域的科研人员参考。

高等有机化学-反应与合成(第五版) 节选

《高等有机化学:反应与合成》(第5版)是《高等有机化学》的新版，自从1977年面世以来，《高等有机化学》作为学科首选教材的地位一直没有动摇过，广泛地覆盖了有机化合物的结构、反应活性及合成。她的第五版相对2001年出版的第四版进行了大幅度的修订，更新了学科发展的相关资料，内容组织更加清晰明朗，特别是计算化学部分。通过控制反应而得到特定的合成是有机合成的全部目标。PartB在不同反应类型的基础上详尽地描述了*常见的和*有用的合成反应。每章后附有习题精选及解答习题的推荐参考文献。